St Germain, Carl Cox and Jean Michel Jarre also feature on the seven-week programme this summer.
Massive Attack will close Just Music Festival in Rome, which runs from June 9th through July 26th.
The Italian festival's second edition will expand upon its debut in 2015, which featured Björk, Carl Cox, Pet Shop Boys and Burt Bacharach playing across four dates. This year's seven-week programme, taking place across four venues in the city, will be launched by Public Enemy at Terrazze Palazzo dei Congressi on June 9th, with St Germain and Nightmares On Wax playing there the following weekend.
Things get clubby when Cox returns to Just Music with Davide Squillace, Jackmaster and Cirillo all sharing a stage on July 1st, with Disclosure and Kerri Chandler billed the next week. Jean Michel Jarre goes solo on the 9th before the pairings continue, including Roisin Murphy and Infinity Ink on the 12th and Thievery Corporation and Federico Aubele on the 20th. Massive Attack's festival-ending set takes place at the Auditorium Parco della Musica on July 26th.